SCOPe 2.07: Domain d1u13a_: 1u13 A:

Lineage for d1u13a_ (1u13 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Cytochrome p450 14 alpha-sterol demethylase (cyp51) [48276] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [48277] (5 PDB entries)
   Uniprot P0A512 P77901

8. Domain d1u13a_: 1u13 A: [107578]
   complexed with hem; mutant

Details for d1u13a_

PDB Entry: 1u13, 2.01 Å

PDB Description: crystal structure analysis of the c37l/c151t/c442a-triple mutant of cyp51 from mycobacterium tuberculosis

PDB Compounds: (A:) cytochrome p450 51

SCOPe Domain Sequences for d1u13a_:

Sequence, based on SEQRES records:

>d1u13a_ a.104.1.1 (A:) Cytochrome p450 14 alpha-sterol demethylase (cyp51) {Mycobacterium tuberculosis [TaxId: 1773]}
savalprvsgghdehghleefrtdpiglmqrvrdelgdvgtfqlagkqvvllsgshanef
ffragdddldqakaypfmtpifgegvvfdasperrkemlhnaalrgeqmkghaatiedqv
rrmiadwgeageidlldffaeltiytssatligkkfrdqldgrfaklyhelergtdplay
vdpylpiesfrrrdearnglvalvadimngrianpptdksdrdmldvliavkaetgtprf
sadeitgmfismmfaghhtssgtaswtlielmrhrdayaavideldelygdgrsvsfhal
rqipqlenvlketlrlhppliilmrvakgefevqghrihegdlvaaspaisnripedfpd
phdfvparyeqprqedllnrwtwipfgagrhrcvgaafaimqikaifsvllreyefemaq
ppesyrndhskmvvqlaqpaavryrrrt

Sequence, based on observed residues (ATOM records):

>d1u13a_ a.104.1.1 (A:) Cytochrome p450 14 alpha-sterol demethylase (cyp51) {Mycobacterium tuberculosis [TaxId: 1773]}
savalprvsgghdehghleefrtdpiglmqrvrdelgdvgtfqlagkqvvllsgshanef
ffragdddldqakaypfmtpifgrrkemlhnaalrgeqmkghaatiedqvrrmiadwgea
geidlldffaeltiytssatligkkfrdqldgrfaklyhelergtdplayvdpylpiesf
rrrdearnglvalvadimngrianpdrdmldvliavkaetgtprfsadeitgmfismmfa
ghhtssgtaswtlielmrhrdayaavideldelygdgrsvsfhalrqipqlenvlketlr
lhppliilmrvakgefevqghrihegdlvaaspaisnripedfpdphdfvparyeqprqe
dllnrwtwipfgagrhrcvgaafaimqikaifsvllreyefemaqppesyrndhskmvvq
laqpaavryrrrt

Timeline for d1u13a_:

• d1u13a_ first appeared in SCOP 1.69
  
• d1u13a_ appears in SCOPe 2.06
  
• d1u13a_ appears in the current release, SCOPe 2.08