SCOPe 2.05: Domain d1tzpb_: 1tzp B:

Lineage for d1tzpb_ (1tzp B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.65: Hedgehog/DD-peptidase [55165] (1 superfamily)
   alpha-beta(2)-alpha-beta(2); 2 layers: alpha/beta

4. Superfamily d.65.1: Hedgehog/DD-peptidase [55166] (5 families)
   zinc-binding motif

5. Family d.65.1.3: MepA-like [111019] (1 protein)
   automatically mapped to Pfam PF03411

6. Protein D-alanyl-D-alanine-endopeptidase MepA [111020] (1 species)

7. Species Escherichia coli [TaxId:562] [111021] (2 PDB entries)
   Uniprot P14007

8. Domain d1tzpb_: 1tzp B: [107521]
   complexed with bu1, so4

Details for d1tzpb_

PDB Entry: 1tzp, 1.4 Å

PDB Description: MEPA, inactive form without ZN in P21

PDB Compounds: (B:) Penicillin-insensitive murein endopeptidase

SCOPe Domain Sequences for d1tzpb_:

Sequence, based on SEQRES records:

>d1tzpb_ d.65.1.3 (B:) D-alanyl-D-alanine-endopeptidase MepA {Escherichia coli [TaxId: 562]}
wqkitqpvpgsaqsigsfsngcivgadtlpiqsehyqvmrtdqrryfghpdlvmfiqrls
sqvsnlgmgtvligdmgmpaggrfngghashqtgldvdiflqlpktrwtsaqllrpqald
lvsrdgkhvvstlwkpeifsliklaaqdkdvtrifvnpaikqqlcldagtdrdwlrkvrp
wfqhrahmhvrlrcpadslecedqplppsgdgcgaelqswfeppkpgttkpekktppplp
pscqalldeh

Sequence, based on observed residues (ATOM records):

>d1tzpb_ d.65.1.3 (B:) D-alanyl-D-alanine-endopeptidase MepA {Escherichia coli [TaxId: 562]}
wqkitqpvpgsaqsigsfsngcivgadtlpiqsehyqvmrtdqrryfghpdlvmfiqrls
sqvsnlgmgtvligdmgmpaggrfngghashqtgldvdiflqlpktrwtsaqllrpqald
lvsrdgkhvvstlwkpeifsliklaaqdkdvtrifvnpaikqqlcldagtdrdwlrkvrp
wfqhrahmhvrlrcpadslecedqplppsgdgcgaelqswfepplppscqalldeh

Timeline for d1tzpb_:

• d1tzpb_ first appeared in SCOP 1.69
  
• d1tzpb_ appears in SCOPe 2.04
  
• d1tzpb_ appears in SCOPe 2.06
  
• d1tzpb_ appears in the current release, SCOPe 2.08