SCOPe 2.08: Domain d1tzda_: 1tzd A:

Lineage for d1tzda_ (1tzd A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.143: SAICAR synthase-like [56103] (1 superfamily)
   consists of two alpha+beta subdomains

4. Superfamily d.143.1: SAICAR synthase-like [56104] (4 families)
   shares functional and structural similarities with the ATP-grasp fold and protein kinase superfamilies

5. Family d.143.1.3: Inositol polyphosphate kinase (IPK) [111188] (2 proteins)
   Pfam PF03770

6. Protein Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A [111189] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [111191] (1 PDB entry)
   Uniprot P17105 203-458

8. Domain d1tzda_: 1tzd A: [107474]
   complexed with adp, mg

Details for d1tzda_

PDB Entry: 1tzd, 2.2 Å

PDB Description: crystal structure of the catalytic core of inositol 1,4,5- trisphosphate 3-kinase

PDB Compounds: (A:) inositol-trisphosphate 3-kinase a

SCOPe Domain Sequences for d1tzda_:

Sequence, based on SEQRES records:

>d1tzda_ d.143.1.3 (A:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Norway rat (Rattus norvegicus) [TaxId: 10116]}
glilkrssepehycmvrlmadvlrgcvpafhgvverdgesylqlqdlldgfdgpcvldck
mgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprymqwregiss
sttlgfriegikkadgscstdfkttrsreqvtrvfeefmqgdaevlkrylnrlqqirdtl
eisdffrrhevigssllfvhdhchragvwlidfgkttplpngqildhrrpweegnredgy
llgldnligilanlae

Sequence, based on observed residues (ATOM records):

>d1tzda_ d.143.1.3 (A:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Norway rat (Rattus norvegicus) [TaxId: 10116]}
glilkrssepehycmvrlmadvlrgcvpafhgvvlqlqdlldgfdgpcvldckmgvrtyl
eeeltkarerpklrkdmykkmlavdpeapteeehaprymqwregisssttlgfriegikk
adgscstdfkttrsreqvtrvfeefmqgdaevlkrylnrlqqirdtleisdffrrhevig
ssllfvhdhchragvwlidfgkttplpngqildhrrpweegnredgyllgldnligilan
lae

Timeline for d1tzda_:

• d1tzda_ first appeared in SCOP 1.69
  
• d1tzda_ appears in SCOPe 2.07