SCOPe 2.05: Domain d1tx2a_: 1tx2 A:

Lineage for d1tx2a_ (1tx2 A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.21: Dihydropteroate synthetase-like [51717] (3 families)

5. Family c.1.21.1: Dihydropteroate synthetase [51718] (2 proteins)

6. Protein Dihydropteroate synthetase [51719] (4 species)

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [102103] (32 PDB entries)
   Uniprot Q81VW8

8. Domain d1tx2a_: 1tx2 A: [107420]
   complexed with 680, so4

Details for d1tx2a_

PDB Entry: 1tx2, 1.83 Å

PDB Description: dihydropteroate synthetase, with bound inhibitor manic, from bacillus anthracis

PDB Compounds: (A:) DHPS, Dihydropteroate synthase

SCOPe Domain Sequences for d1tx2a_:

Sequence, based on SEQRES records:

>d1tx2a_ c.1.21.1 (A:) Dihydropteroate synthetase {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
kwdydlrcgeytlnlnektlimgilnvtpdsfsdggsynevdaavrhakemrdegahiid
iggestrpgfakvsveeeikrvvpmiqavskevklpisidtykaevakqaieagahiind
iwgakaepkiaevaahydvpiilmhnrdnmnyrnlmadmiadlydsikiakdagvrdeni
ildpgigfaktpeqnleamrnleqlnvlgypvllgtsrksfighvldlpveerlegtgat
vclgiekgcefvrvhdvkemsrmakmmdamigk

Sequence, based on observed residues (ATOM records):

>d1tx2a_ c.1.21.1 (A:) Dihydropteroate synthetase {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
kwdydlrcgeytlnlnektlimgilnvtpdsfsdggsynevdaavrhakemrdegahiid
iggesfakvsveeeikrvvpmiqavskevklpisidtykaevakqaieagahiindiwga
kaepkiaevaahydvpiilmhnrdnmnyrnlmadmiadlydsikiakdagvrdeniildp
gigfaktpeqnleamrnleqlnvlgypvllgtsrksfighvldlpveerlegtgatvclg
iekgcefvrvhdvkemsrmakmmdamigk

Timeline for d1tx2a_:

• d1tx2a_ first appeared in SCOP 1.69
  
• d1tx2a_ appears in SCOPe 2.04
  
• d1tx2a_ appears in SCOPe 2.06
  
• d1tx2a_ appears in the current release, SCOPe 2.08