SCOPe 2.03: Domain d1tw8a_: 1tw8 A:

Lineage for d1tw8a_ (1tw8 A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (34 families)

5. Family c.52.1.19: Restriction endonuclease HincII [69525] (1 protein)
   automatically mapped to Pfam PF09226

6. Protein Restriction endonuclease HincII [69526] (1 species)

7. Species Haemophilus influenzae [TaxId:727] [69527] (18 PDB entries)
   Uniprot P17743 ! Uniprot P44413

8. Domain d1tw8a_: 1tw8 A: [107377]
   protein/DNA complex; complexed with ca, na

Details for d1tw8a_

PDB Entry: 1tw8, 2.8 Å

PDB Description: hincii bound to ca2+ and cognate dna gtcgac

PDB Compounds: (A:) Hinc II endonuclease

SCOPe Domain Sequences for d1tw8a_:

Sequence; same for both SEQRES and ATOM records:

>d1tw8a_ c.52.1.19 (A:) Restriction endonuclease HincII {Haemophilus influenzae [TaxId: 727]}
sfikpiyqdinsiligqkvkrpksgtlsghaagepfeklvykflkenlsdltfkqyeyln
dlfmknpaiighearyklfnsptllfllsrgkaatenwsienlfeekqndtadillvkdq
fyelldvktrnisksaqapniisayklaqtcakmidnkefdlfdinylevdwelngedlv
cvstsfaelfksepselyinwaaamqiqfhvrdldqgfngtreewaksylkhfvtqaeqr
aismidkfvkpfkkyil

Timeline for d1tw8a_:

• d1tw8a_ first appeared in SCOP 1.69
  
• d1tw8a_ appears in SCOPe 2.02
  
• d1tw8a_ appears in SCOPe 2.04
  
• d1tw8a_ appears in the current release, SCOPe 2.08