SCOPe 2.08: Domain d1tq4a_: 1tq4 A:

Lineage for d1tq4a_ (1tq4 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Interferon-inducible GTPase [110546] (1 species)
   G domain is inserted in all-alpha domain

7. Species Mouse (Mus musculus) [TaxId:10090] [110547] (5 PDB entries)
   Uniprot Q9QZ85 # all-alpha domain (14-68,252-415)

8. Domain d1tq4a_: 1tq4 A: [107201]
   complexed with gdp, mg
   has additional subdomain(s) that are not in the common domain

Details for d1tq4a_

PDB Entry: 1tq4, 1.95 Å

PDB Description: crystal structure of iigp1: a paradigm for interferon inducible p47 resistance gtpases

PDB Compounds: (A:) interferon-inducible GTPase

SCOPe Domain Sequences for d1tq4a_:

Sequence, based on SEQRES records:

>d1tq4a_ c.37.1.8 (A:) Interferon-inducible GTPase {Mouse (Mus musculus) [TaxId: 10090]}
ndlpssftgyfkkfntgrkiisqeilnlielrmragniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnipnvvfwdlpgigst
nfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditnea
dgepqtfdkekvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpi
ykrhnfmvslpnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksm
kfyrtvfgvdetslqrlardweievdqveamikspavfkptdeetiqerlsryiqefcla
ngyllpknsflkeifylkyyfldmvtedaktllkeiclrn

Sequence, based on observed residues (ATOM records):

>d1tq4a_ c.37.1.8 (A:) Interferon-inducible GTPase {Mouse (Mus musculus) [TaxId: 10090]}
ndlpssftgyfkkfntgrkiisqeilnlielrmragniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvmerhpykhpnipnvvfwdlpgigstnfpp
dtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditneadgep
qtfdkekvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpiykrh
nfmvslpnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksmkfyr
tvfgvdetslqrlardweievdqveamikspavfkptdeetiqerlsryiqefclangyl
lpknsflkeifylkyyfldmvtedaktllkeiclrn

Timeline for d1tq4a_:

• d1tq4a_ first appeared in SCOP 1.69
  
• d1tq4a_ appears in SCOPe 2.07