SCOPe 2.08: Domain d1tq2a1: 1tq2 A:14-411

Lineage for d1tq2a1 (1tq2 A:14-411)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Interferon-inducible GTPase [110546] (1 species)
   G domain is inserted in all-alpha domain

7. Species Mouse (Mus musculus) [TaxId:10090] [110547] (5 PDB entries)
   Uniprot Q9QZ85 # all-alpha domain (14-68,252-415)

8. Domain d1tq2a1: 1tq2 A:14-411 [107199]
   Other proteins in same PDB: d1tq2a2, d1tq2b2
   complexed with gnp, mg, mpd
   has additional subdomain(s) that are not in the common domain

Details for d1tq2a1

PDB Entry: 1tq2, 2.7 Å

PDB Description: Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases

PDB Compounds: (A:) interferon-inducible GTPase

SCOPe Domain Sequences for d1tq2a1:

Sequence, based on SEQRES records:

>d1tq2a1 c.37.1.8 (A:14-411) Interferon-inducible GTPase {Mouse (Mus musculus) [TaxId: 10090]}
ndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnipnvvfwdlpgigst
nfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditnea
dgkpqtfdkekvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpi
ykrhnfmvslpnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksm
kfyrtvfgvdetslqrlardweievdqveamikspavfkptdeetiqerlsryiqefcla
ngyllpknsflkeifylkyyfldmvtedaktllkeicl

Sequence, based on observed residues (ATOM records):

>d1tq2a1 c.37.1.8 (A:14-411) Interferon-inducible GTPase {Mouse (Mus musculus) [TaxId: 10090]}
ndlpssftgyfkkfntgrkiisqeilnlielrmrkgniqltnsaisdalkeidssvlnva
vtgetgsgkssfintlrgigneeegaaktgvvevtmerhpykhpnipnvvfwdlpgigst
nfppdtylekmkfyeydffiiisatrfkkndidiakaismmkkefyfvrtkvdsditnea
dkekvlqdirlncvntfrengiaeppifllsnknvchydfpvlmdklisdlpiykrhnfm
vslpnitdsviekkrqflkqriwlegfaadlvniipsltflldsdletlkksmkfyrtvf
gvdetslqrlardweievdqveamikspavfkptdeetiqerlsryiqefclangyllpk
nsflkeifylkyyfldmvtedaktllkeicl

Timeline for d1tq2a1:

• d1tq2a1 first appeared in SCOP 1.69, called d1tq2a_
  
• d1tq2a1 appears in SCOPe 2.07