SCOP 1.73: Domain d1tk8a2: 1tk8 A:211-704

Lineage for d1tk8a2 (1tk8 A:211-704)

1. Root: SCOP 1.73

2. Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (4 proteins)

6. Protein T7 phage DNA polymerase [56678] (1 species)

7. Species Bacteriophage T7 [TaxId:10760] [56679] (16 PDB entries)

8. Domain d1tk8a2: 1tk8 A:211-704 [107080]
   Other proteins in same PDB: d1tk8a1, d1tk8b_
   complexed with 1pe, 2da, 8og, d3t, mes, mg, so4

Details for d1tk8a2

PDB Entry: 1tk8, 2.5 Å

PDB Description: T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site

PDB Compounds: (A:) DNA polymerase

SCOP Domain Sequences for d1tk8a2:

Sequence, based on SEQRES records:

>d1tk8a2 e.8.1.1 (A:211-704) T7 phage DNA polymerase {Bacteriophage T7 [TaxId: 10760]}
leavdiehraawllakqerngfpfdtkaieelyvelaarrsellrkltetfgswyqpkgg
temfchprtgkplpkypriktpkvggifkkpknkaqregrepceldtreyvagapytpve
hvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlikeyl
miqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspygeq
craafgaehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtknq
iaaelptrdnaktfiygflygagdekigqivgagkergkelkkkflentpaiaalresiq
qtlvessqwvageqqvkwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikte
emlvekglkhgwdgdfaymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrcll
dtegkmgpnwaich

Sequence, based on observed residues (ATOM records):

>d1tk8a2 e.8.1.1 (A:211-704) T7 phage DNA polymerase {Bacteriophage T7 [TaxId: 10760]}
leavdiehraawllakqerngfpfdtkaieelyvelaarrsellrkltetfgswyqpkgg
temfchprtgkplpkypriktpkvggifkkpknkaqregrepceldtreyvagapytpve
hvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlikeyl
miqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspygeq
craafgaehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtknq
iaaelptrdnaktfiygflygagdekigqivgagkergkelkkkflentpaiaalresiq
qtlvessqqvkwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikteemlvek
glkhgwdgdfaymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrclldtegkm
gpnwaich

Timeline for d1tk8a2:

• d1tk8a2 first appeared in SCOP 1.69
  
• d1tk8a2 appears in SCOP 1.71
  
• d1tk8a2 appears in SCOP 1.75
  
• d1tk8a2 appears in the current release, SCOPe 2.08