SCOPe 2.06: Domain d1th1b_: 1th1 B:

Lineage for d1th1b_ (1th1 B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (26 families)

5. Family a.118.1.1: Armadillo repeat [48372] (7 proteins)
   this is a repeat family; one repeat unit is 1ee4 A:288-330 found in domain

6. Protein beta-Catenin [48373] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48375] (8 PDB entries)
   Uniprot P35222 145-664

8. Domain d1th1b_: 1th1 B: [106906]
   complex with a phosphorylated apc 20aa repeat fragment (Uniprot P25054 1468-1529), chains C and D

Details for d1th1b_

PDB Entry: 1th1, 2.5 Å

PDB Description: Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment

PDB Compounds: (B:) beta-catenin

SCOPe Domain Sequences for d1th1b_:

Sequence, based on SEQRES records:

>d1th1b_ a.118.1.1 (B:) beta-Catenin {Human (Homo sapiens) [TaxId: 9606]}
aelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqnt
ndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllh
qegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalv
nimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtl
rnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggie
alvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwp
likatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsmggtqqqfvegvr
meeivegctgalhilardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdk
eaaeaieaegatapltellhsrnegvatyaaavlfrmse

Sequence, based on observed residues (ATOM records):

>d1th1b_ a.118.1.1 (B:) beta-Catenin {Human (Homo sapiens) [TaxId: 9606]}
aelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqnt
ndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllh
qegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalv
nimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtl
rnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggie
alvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwp
likatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsqfvegvrmeeive
gctgalhilardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeai
eaegatapltellhsrnegvatyaaavlfrmse

Timeline for d1th1b_:

• d1th1b_ first appeared in SCOP 1.69
  
• d1th1b_ appears in SCOPe 2.05
  
• d1th1b_ appears in SCOPe 2.07
  
• d1th1b_ appears in the current release, SCOPe 2.08