SCOP 1.73: Domain d1tc0b_: 1tc0 B:

Lineage for d1tc0b_ (1tc0 B:)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (1 protein)

6. Protein HSP90 [55876] (3 species)

7. Species Dog (Canis familiaris) [TaxId:9615] [103225] (20 PDB entries)

8. Domain d1tc0b_: 1tc0 B: [106751]
   complexed with atp, mg, pg4

Details for d1tc0b_

PDB Entry: 1tc0, 2.2 Å

PDB Description: ligand induced conformational shifts in the n-terminal domain of grp94, open conformation complexed with the physiological partner atp

PDB Compounds: (B:) Endoplasmin

SCOP Domain Sequences for d1tc0b_:

Sequence, based on SEQRES records:

>d1tc0b_ d.122.1.1 (B:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
fqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvkik
cdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseligqfgv
gfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasd
yleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

Sequence, based on observed residues (ATOM records):

>d1tc0b_ d.122.1.1 (B:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
fqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvkik
cdkeknllhvtdtgvgmtreelvknltseligqfgvgfysaflvadkvivtskhnndtqh
iwesdsnefsviadprgntlgrgttitlvlkeeasdyleldtiknlvkkysqfinfpiyv
wsskttvwdwelmn

Timeline for d1tc0b_:

• d1tc0b_ first appeared in SCOP 1.69
  
• d1tc0b_ appears in SCOP 1.71
  
• d1tc0b_ appears in SCOP 1.75
  
• d1tc0b_ appears in the current release, SCOPe 2.08