Lineage for d1tbma_ (1tbm A:)

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 546038Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 546039Superfamily a.211.1: HD-domain/PDEase-like [109604] (3 families) (S)
  5. 546057Family a.211.1.2: PDEase [48548] (6 proteins)
    Pfam 00233; multihelical; can be divided into three subdomains
  6. 546163Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (1 species)
  7. 546164Species Human (Homo sapiens) [TaxId:9606] [109943] (1 PDB entry)
  8. 546165Domain d1tbma_: 1tbm A: [106744]

Details for d1tbma_

PDB Entry: 1tbm (more details), 2.23 Å

PDB Description: Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor IBMX binding

SCOP Domain Sequences for d1tbma_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1tbma_ a.211.1.2 (A:) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens)}
ptypkyllspetiealrkptfdvwlwepnemlsclehmyhdlglvrdfsinpvtlrrwlf
cvhdnyrnnpfhnfrhcfcvaqmmysmvwlcslqekfsqtdililmtaaichdldhpgyn
ntyqinartelavryndisplenhhcavafqilaepecnifsnippdgfkqirqgmitli
latdmarhaeimdsfkekmenfdysneehmtllkmilikccdisnevrpmevaepwvdcl
leeyfmqsdrekseglpvapfmdrdkvtkataqigfikfvlipmfetvtklfpmveeiml
qplwesrdryeelkriddamkelqkk

SCOP Domain Coordinates for d1tbma_:

Click to download the PDB-style file with coordinates for d1tbma_.
(The format of our PDB-style files is described here.)

Timeline for d1tbma_:

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d1tbmb_