SCOP 1.71: Domain d1tbba_: 1tbb A:

Lineage for d1tbba_ (1tbb A:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (3 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam 00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (11 PDB entries)

8. Domain d1tbba_: 1tbb A: [106741]

Details for d1tbba_

PDB Entry: 1tbb, 1.6 Å

PDB Description: Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Rolipram

SCOP Domain Sequences for d1tbba_:

Sequence, based on SEQRES records:

>d1tbba_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens)}
qedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlitylm
tledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpgv
snqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvidi
vlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkplq
lyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwadl
vhpdaqdildtlednrewyqstip

Sequence, based on observed residues (ATOM records):

>d1tbba_ a.211.1.2 (A:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens)}
qedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlitylm
tledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhpgv
snqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvidi
vlatdmskhmnlladlktmvetkkvtvllldnysdriqvlqnmvhcadlsnptkplqlyr
qwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwadlvhp
daqdildtlednrewyqstip

Timeline for d1tbba_:

• d1tbba_ first appeared in SCOP 1.69
  
• d1tbba_ appears in SCOP 1.73
  
• d1tbba_ appears in the current release, SCOPe 2.08