SCOP 1.75: Domain d1tb6i_: 1tb6 I:

Lineage for d1tb6i_ (1tb6 I:)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (1 family)

5. Family e.1.1.1: Serpins [56575] (16 proteins)

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (25 PDB entries)
   Uniprot P01008

8. Domain d1tb6i_: 1tb6 I: [106738]
   Other proteins in same PDB: d1tb6.1
   complexed with fuc, gu0, gu1, gu2, gu3, gu4, gu5, gu6, gu8, gu9, man, mpd, nag; mutant

Details for d1tb6i_

PDB Entry: 1tb6, 2.5 Å

PDB Description: 2.5a crystal structure of the antithrombin-thrombin-heparin ternary complex

PDB Compounds: (I:) antithrombin-III

SCOP Domain Sequences for d1tb6i_:

Sequence, based on SEQRES records:

>d1tb6i_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
pvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfy
qhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfff
aklncrlyrkankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsr
aainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykad
gescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpev
lqewldeleemmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddly
vsdafhkaflevneegseaaastavviagrslnpnrvcfkanrpflvfirevplntiifm
grvanpcv

Sequence, based on observed residues (ATOM records):

>d1tb6i_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
pvdictakprdipmnpmciyrspeqkipeatnrrvwelskansrfattfyqhladskndn
dniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrk
ankasklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
tegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmy
qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
mmlcvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkafl
evneegtavviagrslnpnrvcfkanrpflvfirevplntiifmgrvanpcv

Timeline for d1tb6i_:

• d1tb6i_ first appeared in SCOP 1.69
  
• d1tb6i_ appears in SCOP 1.73
  
• d1tb6i_ appears in SCOPe 2.01
  
• d1tb6i_ appears in the current release, SCOPe 2.08