SCOP 1.69: Domain d1t9ra_: 1t9r A:

Lineage for d1t9ra_ (1t9r A:)

1. Root: SCOP 1.69

2. Class a: All alpha proteins [46456] (218 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (2 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   multihelical; can be divided into three subdomains
   3',5'-cyclic-nucleotide phosphodiesterase, Pfam 00233

6. Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101440] (7 PDB entries)

8. Domain d1t9ra_: 1t9r A: [106725]

Details for d1t9ra_

PDB Entry: 1t9r, 2.1 Å

PDB Description: Catalytic Domain Of Human Phosphodiesterase 5A

SCOP Domain Sequences for d1t9ra_:

Sequence, based on SEQRES records:

>d1t9ra_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
eeetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhe
vlcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalsh
dldhrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeykttl
kiikqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwp
iqqriaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealt
hvsedcfplldgcrknrqkwqalaeqqek

Sequence, based on observed residues (ATOM records):

>d1t9ra_ a.211.1.2 (A:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens)}
eeetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhe
vlcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalsh
dldhlaqlychsimehhhfdqclmilnspgnqilsglsieeykttlkiikqailatdlal
yikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriaelvateff
dqlmnrekknkipsmqvgfidaiclqlyealthvsedcfplldgcrknrqkwqalaeqqe
k

Timeline for d1t9ra_:

• d1t9ra_ is new in SCOP 1.69
  
• d1t9ra_ appears in SCOP 1.71
  
• d1t9ra_ appears in the current release, SCOPe 2.08