Lineage for d1t8ub1 (1t8u B:139-406)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2865683Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2865684Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families) (S)
    division into families based on beta-sheet topologies
  5. 2866454Family c.37.1.5: PAPS sulfotransferase [52575] (15 proteins)
    Pfam PF00685
    similar to the nucleotide/nucleoside kinases but transfer sulphate group
  6. 2866495Protein Heparan sulfate glucosamine 3-O-sulfotransferase 3 [110532] (1 species)
  7. 2866496Species Human (Homo sapiens) [TaxId:9606] [110533] (2 PDB entries)
    Uniprot Q9Y663 139-406 # isoform 3A1; 100% sequence identity to isoform 3B1 domain (Uniprot Q9Y662 133-390)
  8. 2866498Domain d1t8ub1: 1t8u B:139-406 [106688]
    Other proteins in same PDB: d1t8ua2, d1t8ub2
    complexed with a3p, na, so4

Details for d1t8ub1

PDB Entry: 1t8u (more details), 1.95 Å

PDB Description: crystal structure of human 3-o-sulfotransferase-3 with bound pap and tetrasaccharide substrate
PDB Compounds: (B:) heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1

SCOPe Domain Sequences for d1t8ub1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t8ub1 c.37.1.5 (B:139-406) Heparan sulfate glucosamine 3-O-sulfotransferase 3 {Human (Homo sapiens) [TaxId: 9606]}
gtlallldegskqlpqaiiigvkkggtralleflrvhpdvravgaephffdrsydkglaw
yrdlmprtldgqitmektpsyfvtreaparisamskdtklivvvrdpvtraisdytqtls
krpdiptfesltfknrtaglidtswsaiqigiyakhlehwlrhfpirqmlfvsgerlisd
pagelgrvqdflglkriitdkhfyfnktkgfpclkkaegssrphclgktkgrthpeidre
vvrrlrefyrpfnlkfyqmtghdfgwdg

SCOPe Domain Coordinates for d1t8ub1:

Click to download the PDB-style file with coordinates for d1t8ub1.
(The format of our PDB-style files is described here.)

Timeline for d1t8ub1:

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Domains from same chain:
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d1t8ub2