SCOP 1.69: Domain d1t66l1: 1t66 L:1-112

Lineage for d1t66l1 (1t66 L:1-112)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (126 PDB entries)

8. Domain d1t66l1: 1t66 L:1-112 [106551]
   Other proteins in same PDB: d1t66c2, d1t66d1, d1t66d2, d1t66h1, d1t66h2, d1t66l2

Details for d1t66l1

PDB Entry: 1t66, 2.3 Å

PDB Description: The structure of FAB with intermediate affinity for fluorescein.

SCOP Domain Sequences for d1t66l1:

Sequence; same for both SEQRES and ATOM records:

>d1t66l1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
dvvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqsthvpwtfgggtkleik

Timeline for d1t66l1:

• d1t66l1 is new in SCOP 1.69
  
• d1t66l1 appears in SCOP 1.71
  
• d1t66l1 appears in the current release, SCOPe 2.08