SCOP 1.73: Domain d1sxja2: 1sxj A:295-547

Lineage for d1sxja2 (1sxj A:295-547)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.20: Extended AAA-ATPase domain [81269] (27 proteins)
   fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain

6. Protein Replication factor C1 [110566] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [110567] (1 PDB entry)

8. Domain d1sxja2: 1sxj A:295-547 [106082]
   Other proteins in same PDB: d1sxja1, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf1, d1sxjf2, d1sxjg1, d1sxjg2, d1sxjh1, d1sxjh2
   complexed with adp, atg, mg; mutant

Details for d1sxja2

PDB Entry: 1sxj, 2.85 Å

PDB Description: crystal structure of the eukaryotic clamp loader (replication factor c, rfc) bound to the dna sliding clamp (proliferating cell nuclear antigen, pcna)

PDB Compounds: (A:) Activator 1 95 kDa subunit

SCOP Domain Sequences for d1sxja2:

Sequence, based on SEQRES records:

>d1sxja2 c.37.1.20 (A:295-547) Replication factor C1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
dklwtvkyaptnlqqvcgnkgsvmklknwlanwenskknsfkhagkdgsgvfraamlygp
pgigkttaahlvaqelgydileqnasdvrsktllnagvknaldnmsvvgyfkhneeaqnl
ngkhfviimdevdgmsggdrggvgqlaqfcrktstplilicnernlpkmrpfdrvcldiq
frrpdansiksrlmtiairekfkldpnvidrliqttrgdirqvinllstistttktinhe
nineiskawekni

Sequence, based on observed residues (ATOM records):

>d1sxja2 c.37.1.20 (A:295-547) Replication factor C1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
dklwtvkyaptnlqqvcgnkgsvmklknwlanwenskknsfkhagkdgsgvfraamlygp
pgigkttaahlvaqelgydileqnasdvrsktllnagvknaldnmsvvgyfkhqnlngkh
fviimdevdgmsggdrggvgqlaqfcrktstplilicnernlpkmrpfdrvcldiqfrrp
dansiksrlmtiairekfkldpnvidrliqttrgdirqvinllstistttktinhenine
iskawekni

Timeline for d1sxja2:

• d1sxja2 first appeared in SCOP 1.69
  
• d1sxja2 appears in SCOP 1.71
  
• d1sxja2 appears in SCOP 1.75
  
• d1sxja2 appears in the current release, SCOPe 2.08