SCOP 1.75: Domain d1sr5a_: 1sr5 A:

Lineage for d1sr5a_ (1sr5 A:)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (1 family)

5. Family e.1.1.1: Serpins [56575] (16 proteins)

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (25 PDB entries)
   Uniprot P01008

8. Domain d1sr5a_: 1sr5 A: [105952]
   Other proteins in same PDB: d1sr5.1
   complexed with nag, nt1, nt2

Details for d1sr5a_

PDB Entry: 1sr5, 3.1 Å

PDB Description: antithrombin-anhydrothrombin-heparin ternary complex structure

PDB Compounds: (A:) antithrombin-III

SCOP Domain Sequences for d1sr5a_:

Sequence, based on SEQRES records:

>d1sr5a_ e.1.1.1 (A:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
vdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyq
hladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffa
klncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsra
ainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadg
escsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevl
qewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyv
sdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmg
rvanpcv

Sequence, based on observed residues (ATOM records):

>d1sr5a_ e.1.1.1 (A:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
vdictakprdipmnpmciyrspqkipeatnrrvwelskansrfattfyqhladskndndn
iflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkan
kssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnkte
gritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqe
gkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemm
lvvhmprfriedgfslkeqlqdmglvdlfspeksklpgiddlyvsdafhkaflevneega
aastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv

Timeline for d1sr5a_:

• d1sr5a_ first appeared in SCOP 1.69
  
• d1sr5a_ appears in SCOP 1.73
  
• d1sr5a_ appears in SCOPe 2.01
  
• d1sr5a_ appears in the current release, SCOPe 2.08