SCOPe 2.08: Domain d1sqnb_: 1sqn B:

Lineage for d1sqnb_ (1sqn B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Progesterone receptor [48517] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48518] (10 PDB entries)
   Uniprot P06401 679-932

8. Domain d1sqnb_: 1sqn B: [105945]
   complexed with ndr

Details for d1sqnb_

PDB Entry: 1sqn, 1.45 Å

PDB Description: progesterone receptor ligand binding domain with bound norethindrone

PDB Compounds: (B:) progesterone receptor

SCOPe Domain Sequences for d1sqnb_:

Sequence, based on SEQRES records:

>d1sqnb_ a.123.1.1 (B:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
lipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfrnl
hiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslcltmw
qipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrqkg
vvsssqrfyqltklldnlhdlvkqlhlyclntfiqsralsvefpemmseviaaqlpkila
gmvkpllfhkk

Sequence, based on observed residues (ATOM records):

>d1sqnb_ a.123.1.1 (B:) Progesterone receptor {Human (Homo sapiens) [TaxId: 9606]}
lipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfrnl
hiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslcltmw
qipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrqgv
vsssqrfyqltklldnlhdlvkqlhlyclntfiqsralsvefpemmseviaaqlpkilag
mvkpllfhkk

Timeline for d1sqnb_:

• d1sqnb_ first appeared in SCOP 1.69
  
• d1sqnb_ appears in SCOPe 2.07