SCOP 1.69: Domain d1sqia1: 1sqi A:8-156

Lineage for d1sqia1 (1sqi A:8-156)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.32: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1 superfamily)
   beta-alpha-beta(3); 2 layers: alpha/beta

4. Superfamily d.32.1: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54593] (8 families)

5. Family d.32.1.3: Extradiol dioxygenases [54602] (4 proteins)
   duplication: consists of 2 similar domains with 2 repeats in each
   Similar to the Methylmalonyl-CoA epimerase dimer

6. Protein 4-hydroxyphenylpyruvate dioxygenase, HppD [54608] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [110878] (1 PDB entry)

8. Domain d1sqia1: 1sqi A:8-156 [105914]

Details for d1sqia1

PDB Entry: 1sqi, 2.15 Å

PDB Description: Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

SCOP Domain Sequences for d1sqia1:

Sequence; same for both SEQRES and ATOM records:

>d1sqia1 d.32.1.3 (A:8-156) 4-hydroxyphenylpyruvate dioxygenase, HppD {Human (Homo sapiens)}
gpkpergrflhfhsvtfwvgnakqaasfycnkmgfeplaykgletgsrevvshvikqgki
vfvlcsalnpwnkemgdhlvkhgdgvkdiafevedcehivqkarergakivrepwveedk
fgkvkfavlqtygdtthtlvekinytgrf

Timeline for d1sqia1:

• d1sqia1 is new in SCOP 1.69
  
• d1sqia1 appears in SCOP 1.71
  
• d1sqia1 appears in the current release, SCOPe 2.08