SCOPe 2.08: Domain d1smia_: 1smi A:

Lineage for d1smia_ (1smi A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Cytochrome P450 bm-3 [48268] (2 species)

7. Species Bacillus megaterium [TaxId:1404] [48269] (108 PDB entries)
   Uniprot P14779

8. Domain d1smia_: 1smi A: [105758]
   complexed with hem; mutant

Details for d1smia_

PDB Entry: 1smi, 2 Å

PDB Description: a single mutation of p450 bm3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme

PDB Compounds: (A:) bifunctional p-450:nadph-p450 reductase

SCOPe Domain Sequences for d1smia_:

Sequence, based on SEQRES records:

>d1smia_ a.104.1.1 (A:) Cytochrome P450 bm-3 {Bacillus megaterium [TaxId: 1404]}
tikempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapgrvtrylssqrlike
acdesrfdknlsqalkfvrdfagdglftswtheknwkkahnillpsfsqqamkgyhammv
diavqlvqkwerlnadehievpedmtrltldtiglcgfnyrfnsfyrdqphpfitsmvra
ldeamnklqranpddpaydenkrqfqedikvmndlvdkiiadrkasgeqsddllthmlng
kdpetgeplddeniryqiitflieghettsgllsfalyflvknphvlqkaaeeaarvlvd
pvpsykqvkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipql
hrdktiwgddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlgmmlkh
fdfedhtnyeldiketltlkpegfvvkakskkiplg

Sequence, based on observed residues (ATOM records):

>d1smia_ a.104.1.1 (A:) Cytochrome P450 bm-3 {Bacillus megaterium [TaxId: 1404]}
tikempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapgrvtrylssqrlike
acdesrfdknlsqalkfvrdfagdglftswtheknwkkahnillpsfqqamkgyhammvd
iavqlvqkwerlnadehievpedmtrltldtiglcgfnyrfnsfyrdqphpfitsmvral
deamnklqranqfqedikvmndlvdkiiadrkaddllthmlngkdpetgeplddeniryq
iitflieghettsgllsfalyflvknphvlqkaaeeaarvlvdpvpsykqvkqlkyvgmv
lnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwgddveefrpe
rfenpsaipqhafkpfgngqracigqqfalheatlvlgmmlkhfdfedhtnyeldiketl
tlkpegfvvkakskkiplg

Timeline for d1smia_:

• d1smia_ first appeared in SCOP 1.69
  
• d1smia_ appears in SCOPe 2.07