SCOPe 2.01: Domain d1shyb1: 1shy B:40-515

Lineage for d1shyb1 (1shy B:40-515)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.69: 7-bladed beta-propeller [50964] (14 superfamilies)
   consists of seven 4-stranded beta-sheet motifs; meander

4. Superfamily b.69.12: Sema domain [101912] (1 family)
   irregular 7-bladed beta-propeller with a large insertion in the fifth blade

5. Family b.69.12.1: Sema domain [101913] (3 proteins)
   Pfam PF01403

6. Protein Hepatocyte growth factor receptor [110292] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [110293] (1 PDB entry)
   Uniprot P08581 40-564

8. Domain d1shyb1: 1shy B:40-515 [105565]
   Other proteins in same PDB: d1shya_, d1shyb2

Details for d1shyb1

PDB Entry: 1shy, 3.22 Å

PDB Description: the crystal structure of hgf beta-chain in complex with the sema domain of the met receptor.

PDB Compounds: (B:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d1shyb1:

Sequence, based on SEQRES records:

>d1shyb1 b.69.12.1 (B:40-515) Hepatocyte growth factor receptor {Human (Homo sapiens) [TaxId: 9606]}
kyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlehpdcfpcq
dcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrhvfphnhtadiqsevh
cifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinssyfpdhplhsisvrrl
ketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltvqretldaqtfhtrii
rfcsinsglhsymempleciltelvprgstkkevfnilqaayvskpgaqlarqigaslnd
dilfgvfaqskpdsaepmdrsamcafpikyvndffnkivnknnvrclqhfygpnhehcfn
rtllrnssgcearrdeyrtefttalqrvdlfmgqfsevlltsistfikgdltianlgtse
grfmqvvvsrsgpstphvnflldshpvspevivehtlnqngytlvitgkkitkipl

Sequence, based on observed residues (ATOM records):

>d1shyb1 b.69.12.1 (B:40-515) Hepatocyte growth factor receptor {Human (Homo sapiens) [TaxId: 9606]}
kyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlehpdcfpcq
dcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrhvfphnhtadiqsevh
cifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinssyfpdhplhsisvrrl
ketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltvqretldaqtfhtrii
rfcsinsglhsymempleciltkevfnilqaayvskpgaqlarqigaslnddilfgvfaq
skpdsaepmdrsamcafpikyvndffnkinvrclqhfygpnhehcfnrdeyrtefttalq
rvdlfmgqfsevlltsistfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshp
vspevivehtlnqngytlvitgkkitkipl

Timeline for d1shyb1:

• d1shyb1 first appeared in SCOP 1.69
  
• d1shyb1 appears in SCOP 1.75
  
• d1shyb1 appears in SCOPe 2.02
  
• d1shyb1 appears in the current release, SCOPe 2.08