Lineage for d1shja_ (1shj A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2100990Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2100991Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2100992Family c.17.1.1: Caspase catalytic domain [52130] (8 protein domains)
  6. 2101043Protein Caspase-7 [63961] (1 species)
  7. 2101044Species Human (Homo sapiens) [TaxId:9606] [63962] (12 PDB entries)
    Uniprot P55210 57-303
  8. 2101065Domain d1shja_: 1shj A: [105554]
    complexed with nxn, so4

Details for d1shja_

PDB Entry: 1shj (more details), 2.8 Å

PDB Description: Caspase-7 in complex with DICA allosteric inhibitor
PDB Compounds: (A:) caspase-7

SCOPe Domain Sequences for d1shja_:

Sequence, based on SEQRES records: (download)

>d1shja_ c.17.1.1 (A:) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgarcktlle
kpklffiqacrgtelddgiqadsgpindtdanprykipveadflfaystvpgyyswrspg
rgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhekkqipcvvsmlt
kelyfsq

Sequence, based on observed residues (ATOM records): (download)

>d1shja_ c.17.1.1 (A:) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgarcktlle
kpklffiqacrgteprykipveadflfaystvrgswfvqalcsileehgkdleimqiltr
vndrvarhfkkqipcvvsmltkelyfsq

SCOPe Domain Coordinates for d1shja_:

Click to download the PDB-style file with coordinates for d1shja_.
(The format of our PDB-style files is described here.)

Timeline for d1shja_: