SCOPe 2.01: Domain d1sfq.1: 1sfq A:,B:

Lineage for d1sfq.1 (1sfq A:,B:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50533] (26 PDB entries)
   Uniprot P00734 333-622

8. Domain d1sfq.1: 1sfq A:,B: [105498]
   complexed with 0g6, na, nag; mutant

Details for d1sfq.1

PDB Entry: 1sfq, 1.91 Å

PDB Description: fast form of thrombin mutant r(77a)a bound to ppack

PDB Compounds: (A:) thrombin, (B:) thrombin

SCOPe Domain Sequences for d1sfq.1:

Sequence, based on SEQRES records:

>g1sfq.1 b.47.1.2 (A:,B:) Thrombin {Cow (Bos taurus) [TaxId: 9913]}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Sequence, based on observed residues (ATOM records):

>g1sfq.1 b.47.1.2 (A:,B:) Thrombin {Cow (Bos taurus) [TaxId: 9913]}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwgq
psvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfn
nrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Timeline for d1sfq.1:

• d1sfq.1 first appeared in SCOP 1.69
  
• d1sfq.1 appears in SCOP 1.75
  
• d1sfq.1 appears in SCOPe 2.02
  
• d1sfq.1 appears in the current release, SCOPe 2.08