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Lineage for d1seja2 (1sej A:233-521)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 871398Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 871399Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family) (S)
  5. 871400Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 protein domains)
  6. 871401Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)
  7. 871402Species Cryptosporidium hominis [TaxId:237895] [100887] (4 PDB entries)
  8. 871405Domain d1seja2: 1sej A:233-521 [105456]
    Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
    Q5CGA3 Q27552

Details for d1seja2

PDB Entry: 1sej (more details), 2.87 Å

PDB Description: Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP
PDB Compounds: (A:) Bifunctional dihydrofolate reductase-thymidylate synthase

SCOP Domain Sequences for d1seja2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1seja2 d.117.1.1 (A:233-521) Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain {Cryptosporidium hominis [TaxId: 237895]}
rehyefqyldllsrvlengayrenrtgistysifgqmmrfdmresfpllttkkvairsif
eeliwfikgdtngnhliekkvyiwsgngskeyleriglghreendlgpiygfqwrhynge
yktmhddytgvgvdqlaklietlknnpkdrrhiltawnpsalsqmalppchvlsqyyvtn
dnclscnlyqrscdlglgspfniasyailtmmlaqvcgyepgelaifigdahiyenhltq
lkeqlsrtprpfpqlkfkrkveniedfkwedieligyypyptikmdmav

SCOP Domain Coordinates for d1seja2:

Click to download the PDB-style file with coordinates for d1seja2.
(The format of our PDB-style files is described here.)

Timeline for d1seja2: