Lineage for d1sc3.1 (1sc3 A:,B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2100990Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2100991Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2100992Family c.17.1.1: Caspase catalytic domain [52130] (8 protein domains)
  6. 2101096Protein Interleukin-1beta converting enzyme (a cysteine protease) [52133] (1 species)
  7. 2101097Species Human (Homo sapiens) [TaxId:9606] [52134] (14 PDB entries)
    Uniprot P29466 125-297,317-404
  8. 2101098Domain d1sc3.1: 1sc3 A:,B: [105416]
    complexed with mli; mutant

Details for d1sc3.1

PDB Entry: 1sc3 (more details), 1.8 Å

PDB Description: Crystal structure of the human caspase-1 C285A mutant in complex with malonate
PDB Compounds: (A:) Interleukin-1 beta convertase, (B:) Interleukin-1 beta convertase

SCOPe Domain Sequences for d1sc3.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1sc3.1 c.17.1.1 (A:,B:) Interleukin-1beta converting enzyme (a cysteine protease) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1sc3.1:

Click to download the PDB-style file with coordinates for d1sc3.1.
(The format of our PDB-style files is described here.)

Timeline for d1sc3.1: