SCOP 1.71: Domain d1sb1.1: 1sb1 L:,H:

Lineage for d1sb1.1 (1sb1 L:,H:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50533] (26 PDB entries)

8. Domain d1sb1.1: 1sb1 L:,H: [105407]
   complexed with 165, na

Details for d1sb1.1

PDB Entry: 1sb1, 1.9 Å

PDB Description: Novel Non-Covalent Thrombin Inhibitors Incorporating P1 4,5,6,7-Tetrahydrobenzothiazole Arginine Side Chain Mimetics

SCOP Domain Sequences for d1sb1.1:

Sequence, based on SEQRES records:

>g1sb1.1 b.47.1.2 (L:,H:) Thrombin {Cow (Bos taurus)}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

Sequence, based on observed residues (ATOM records):

>g1sb1.1 b.47.1.2 (L:,H:) Thrombin {Cow (Bos taurus)}
eadcglrplfekksledkterellesyidXivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqps
vlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnr
wyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

Timeline for d1sb1.1:

• d1sb1.1 first appeared in SCOP 1.69
  
• d1sb1.1 appears in SCOP 1.73
  
• d1sb1.1 appears in the current release, SCOPe 2.08