SCOPe 2.01: Domain d1sa4a_: 1sa4 A:

Lineage for d1sa4a_ (1sa4 A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (20 PDB entries)
   Uniprot P49354

8. Domain d1sa4a_: 1sa4 A: [105402]
   Other proteins in same PDB: d1sa4b_
   complexed with fpp, jan, suc, zn

Details for d1sa4a_

PDB Entry: 1sa4, 2.1 Å

PDB Description: human protein farnesyltransferase complexed with fpp and r115777

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOPe Domain Sequences for d1sa4a_:

Sequence; same for both SEQRES and ATOM records:

>d1sa4a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d1sa4a_:

• d1sa4a_ first appeared in SCOP 1.69
  
• d1sa4a_ appears in SCOP 1.75
  
• d1sa4a_ appears in SCOPe 2.02
  
• d1sa4a_ appears in the current release, SCOPe 2.08