SCOP 1.75: Domain d1s63a_: 1s63 A:

Lineage for d1s63a_ (1s63 A:)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (1 family)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (2 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69093] (20 PDB entries)
   Uniprot P49354

8. Domain d1s63a_: 1s63 A: [105285]
   Other proteins in same PDB: d1s63b_
   complexed with 778, fpp, suc, zn

Details for d1s63a_

PDB Entry: 1s63, 1.9 Å

PDB Description: human protein farnesyltransferase complexed with l-778,123 and fpp

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit

SCOP Domain Sequences for d1s63a_:

Sequence; same for both SEQRES and ATOM records:

>d1s63a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Human (Homo sapiens) [TaxId: 9606]}
fvsldspsyvlyrdraewadidpvpqndgpnpvvqiiysdkfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllkslqkdlheemnyitaiieeqpknyqvwhhrrv
lvewlrdpsqelefiadilnqdaknyhawqhrqwviqefklwdnelqyvdqllkedvrnn
svwnqryfvisnttgyndravlerevqytlemiklvphnesawnylkgilqdrglskypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhst

Timeline for d1s63a_:

• d1s63a_ first appeared in SCOP 1.69
  
• d1s63a_ appears in SCOP 1.73
  
• d1s63a_ appears in SCOPe 2.01
  
• d1s63a_ appears in the current release, SCOPe 2.08