SCOP 1.69: Domain d1s5ih1: 1s5i H:1-113

Lineage for d1s5ih1 (1s5i H:1-113)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 7.1 [TaxId:10090] [88557] (34 PDB entries)

8. Domain d1s5ih1: 1s5i H:1-113 [105272]
   Other proteins in same PDB: d1s5ih2, d1s5il1, d1s5il2

Details for d1s5ih1

PDB Entry: 1s5i, 2.7 Å

PDB Description: fab (lnkb-2) of monoclonal antibody to human interleukin-2, crystal structure

SCOP Domain Sequences for d1s5ih1:

Sequence; same for both SEQRES and ATOM records:

>d1s5ih1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 7.1}
gvqlqesgpglvkpsqslsltctvtgysitsdyawnwirqfpgnklewmgyitysgstgy
npslksrisitrdtsknqfflqlnsvttedtatyycasyddytwftywgqgtlvtvsa

Timeline for d1s5ih1:

• d1s5ih1 is new in SCOP 1.69
  
• d1s5ih1 appears in SCOP 1.71
  
• d1s5ih1 appears in the current release, SCOPe 2.08