Lineage for d1s5hb1 (1s5h B:1-118)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017824Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (181 PDB entries)
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor
  8. 2017890Domain d1s5hb1: 1s5h B:1-118 [105269]
    Other proteins in same PDB: d1s5ha1, d1s5ha2, d1s5hb2, d1s5hc_
    complexed with dga, f09, k; mutant

Details for d1s5hb1

PDB Entry: 1s5h (more details), 2.2 Å

PDB Description: Potassium Channel Kcsa-Fab Complex T75C mutant in K+
PDB Compounds: (B:) antibody fab fragment heavy chain

SCOPe Domain Sequences for d1s5hb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1s5hb1 b.1.1.1 (B:1-118) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qvqlqqpgaelvkpgasvklsckasgytftsdwihwvkqrpghglewigeiipsygrany
nekiqkkatltadkssstafmqlssltsedsavyycarergdgyfavwgagttvtvss

SCOPe Domain Coordinates for d1s5hb1:

Click to download the PDB-style file with coordinates for d1s5hb1.
(The format of our PDB-style files is described here.)

Timeline for d1s5hb1: