Lineage for d1s4yd_ (1s4y D:)

  1. Root: SCOPe 2.07
  2. 2581248Class g: Small proteins [56992] (98 folds)
  3. 2584898Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
    disulfide-rich fold; common core is all-beta
  4. 2584899Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families) (S)
  5. 2584990Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)
  6. 2584991Protein Activin A (Inhibin beta A) [90170] (1 species)
  7. 2584992Species Human (Homo sapiens) [TaxId:9606] [90171] (8 PDB entries)
    Uniprot P08476 311-426
  8. 2584997Domain d1s4yd_: 1s4y D: [105259]
    Other proteins in same PDB: d1s4ya_, d1s4yc_
    Structural genomics target

Details for d1s4yd_

PDB Entry: 1s4y (more details), 2.3 Å

PDB Description: Crystal structure of the activin/actrIIb extracellular domain
PDB Compounds: (D:) Inhibin beta A chain

SCOPe Domain Sequences for d1s4yd_:

Sequence, based on SEQRES records: (download)

>d1s4yd_ g.17.1.2 (D:) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
cdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhstvi
nhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

Sequence, based on observed residues (ATOM records): (download)

>d1s4yd_ g.17.1.2 (D:) Activin A (Inhibin beta A) {Human (Homo sapiens) [TaxId: 9606]}
cdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiafhstvinhyrmrgc
cvptklrpmsmlyyddgqniikkdiqnmiveecgcs

SCOPe Domain Coordinates for d1s4yd_:

Click to download the PDB-style file with coordinates for d1s4yd_.
(The format of our PDB-style files is described here.)

Timeline for d1s4yd_: