Lineage for d1s1xa2 (1s1x A:2-429)

  1. Root: SCOP 1.71
  2. 617324Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)
  3. 618192Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 618193Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 618312Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)
  6. 618313Protein HIV-1 reverse transcriptase [56689] (2 species)
  7. 618314Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (83 PDB entries)
  8. 618404Domain d1s1xa2: 1s1x A:2-429 [105218]
    Other proteins in same PDB: d1s1xa1

Details for d1s1xa2

PDB Entry: 1s1x (more details), 2.8 Å

PDB Description: Crystal structure of V108I mutant HIV-1 reverse transcriptase in complex with nevirapine

SCOP Domain Sequences for d1s1xa2:

Sequence, based on SEQRES records: (download)

>d1s1xa2 e.8.1.2 (A:2-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvf
aikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtildvgdayfsvpld
edfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviy
qymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtv
qpivlpekdswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeael
elaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgah
tndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpp
lvklwyql

Sequence, based on observed residues (ATOM records): (download)

>d1s1xa2 e.8.1.2 (A:2-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvf
aikkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtildvgdayfsvpldedfrk
ytaftipsinnetiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddly
vgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpe
kdswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeaelelaenre
ilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkql
teavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq
l

SCOP Domain Coordinates for d1s1xa2:

Click to download the PDB-style file with coordinates for d1s1xa2.
(The format of our PDB-style files is described here.)

Timeline for d1s1xa2:

View in 3D
Domains from same chain:
(mouse over for more information)
d1s1xa1
View in 3D
Domains from other chains:
(mouse over for more information)
d1s1xb1