Lineage for d1s1vb1 (1s1v B:6-429)

  1. Root: SCOP 1.71
  2. 617324Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)
  3. 618192Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 618193Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 618312Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)
  6. 618313Protein HIV-1 reverse transcriptase [56689] (2 species)
  7. 618314Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (83 PDB entries)
  8. 618363Domain d1s1vb1: 1s1v B:6-429 [105213]
    Other proteins in same PDB: d1s1va1
    complexed with tnk; mutant

Details for d1s1vb1

PDB Entry: 1s1v (more details), 2.6 Å

PDB Description: Crystal structure of L100I mutant HIV-1 reverse transcriptase in complex with TNK-651

SCOP Domain Sequences for d1s1vb1:

Sequence, based on SEQRES records: (download)

>d1s1vb1 e.8.1.2 (B:6-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpagikkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyql

Sequence, based on observed residues (ATOM records): (download)

>d1s1vb1 e.8.1.2 (B:6-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaiks
tkwrklvdfrelnkrtqdfwgiphpagikkkksvtvldvgdayfsvpldedfrkytafti
psinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsd
leigqhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyp
gikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkq
gqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklp
iqketwetwwteywqatwipewefvntpplvklwyql

SCOP Domain Coordinates for d1s1vb1:

Click to download the PDB-style file with coordinates for d1s1vb1.
(The format of our PDB-style files is described here.)

Timeline for d1s1vb1: