Lineage for d1s1ta2 (1s1t A:3-429)

  1. Root: SCOP 1.71
  2. 617324Class e: Multi-domain proteins (alpha and beta) [56572] (48 folds)
  3. 618192Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 618193Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 618312Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)
  6. 618313Protein HIV-1 reverse transcriptase [56689] (2 species)
  7. 618314Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (83 PDB entries)
  8. 618318Domain d1s1ta2: 1s1t A:3-429 [105206]
    Other proteins in same PDB: d1s1ta1

Details for d1s1ta2

PDB Entry: 1s1t (more details), 2.4 Å

PDB Description: Crystal structure of L100I mutant HIV-1 reverse transcriptase in complex with UC-781
PDB Compounds: (A:)

SCOP Domain Sequences for d1s1ta2:

Sequence, based on SEQRES records: (download)

>d1s1ta2 e.8.1.2 (A:3-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfa
ikkkdstkwrklvdfrelnkrtqdfwevqlgiphpagikkkksvtvldvgdayfsvplde
dfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyq
ymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvq
pivlpekdswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeaele
laenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgaht
ndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntppl
vklwyql

Sequence, based on observed residues (ATOM records): (download)

>d1s1ta2 e.8.1.2 (A:3-429) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
spietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfa
ikwrklvdfrelnkrtqdfwevqlgiphpagikkkksvtvldvgdayfsvpldedfrkyt
aftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddly
vgsdleigqhrtkieelrqhllrwglttpkkhqkeppflwmgyelhpdkwtvqpivlpek
dswtvndiqklvgklnwasqiypgikvrqlakllrgtkalteviplteeaelelaenrei
lkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlt
eavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyql

SCOP Domain Coordinates for d1s1ta2:

Click to download the PDB-style file with coordinates for d1s1ta2.
(The format of our PDB-style files is described here.)

Timeline for d1s1ta2:

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Domains from same chain:
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d1s1ta1
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Domains from other chains:
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d1s1tb1