SCOP 1.69: Domain d1roza_: 1roz A:

Lineage for d1roza_ (1roz A:)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.1: Deoxyhypusine synthase, DHS [52468] (1 protein)

6. Protein Deoxyhypusine synthase, DHS [52469] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52470] (4 PDB entries)

8. Domain d1roza_: 1roz A: [105025]

Details for d1roza_

PDB Entry: 1roz, 2.21 Å

PDB Description: Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form

SCOP Domain Sequences for d1roza_:

Sequence; same for both SEQRES and ATOM records:

>d1roza_ c.31.1.1 (A:) Deoxyhypusine synthase, DHS {Human (Homo sapiens)}
stqvrgydfnrgvnyralleafgttgfqatnfgravqqvnamiekkleplsqdedqhadl
tqsrrpltsctiflgytsnlissgiretirylvqhnmvdvlvttaggveedlikclapty
lgefslrgkelrenginrignllvpnenyckfedwlmpildqmvmeqntegvkwtpskmi
arlgkeinnpesvyywaqknhipvfspaltdgslgdmiffhsyknpglvldivedlrlin
tqaifakctgmiilgggvvkhhiananlmrngadyavyintaqefdgsdsgarpdeavsw
gkirvdaqpvkvyadaslvfpllvaetfaqkmdafm

Timeline for d1roza_:

• d1roza_ is new in SCOP 1.69
  
• d1roza_ appears in SCOP 1.71
  
• d1roza_ appears in the current release, SCOPe 2.08