Lineage for d1rlza_ (1rlz A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107257Family c.31.1.1: Deoxyhypusine synthase, DHS [52468] (1 protein)
    automatically mapped to Pfam PF01916
  6. 2107258Protein Deoxyhypusine synthase, DHS [52469] (1 species)
  7. 2107259Species Human (Homo sapiens) [TaxId:9606] [52470] (4 PDB entries)
    Uniprot P49366
  8. 2107263Domain d1rlza_: 1rlz A: [104989]
    complexed with nad

Details for d1rlza_

PDB Entry: 1rlz (more details), 2.15 Å

PDB Description: Deoxyhypusine synthase holoenzyme in its high ionic strength, low pH crystal form
PDB Compounds: (A:) deoxyhypusine synthase

SCOPe Domain Sequences for d1rlza_:

Sequence, based on SEQRES records: (download)

>d1rlza_ c.31.1.1 (A:) Deoxyhypusine synthase, DHS {Human (Homo sapiens) [TaxId: 9606]}
apagalaavlkhsstlppestqvrgydfnrgvnyralleafgttgfqatnfgravqqvna
miekkleplsqdedqhadltqsrrpltsctiflgytsnlissgiretirylvqhnmvdvl
vttaggveedlikclaptylgefslrgkelrenginrignllvpnenyckfedwlmpild
qmvmeqntegvkwtpskmiarlgkeinnpesvyywaqknhipvfspaltdgslgdmiffh
syknpglvldivedlrlintqaifakctgmiilgggvvkhhiananlmrngadyavyint
aqefdgsdsgarpdeavswgkirvdaqpvkvyadaslvfpllvaetfaqkmdafmhekne
d

Sequence, based on observed residues (ATOM records): (download)

>d1rlza_ c.31.1.1 (A:) Deoxyhypusine synthase, DHS {Human (Homo sapiens) [TaxId: 9606]}
apagalaavlkhsstlppestqvrgydfnrgvnyralleafgttgfqatnfgravqqvna
miekklepltsctiflgytsnlissgiretirylvqhnmvdvlvttaggveedlikclap
tylgefslrgkelrenginrignllvpnenyckfedwlmpildqmvmeqntegvkwtpsk
miarlgkeinnpesvyywaqknhipvfspaltdgslgdmiffhsyknpglvldivedlrl
intqaifakctgmiilgggvvkhhiananlmrngadyavyintaqefdgsdsgarpdeav
swgkirvdaqpvkvyadaslvfpllvaetfaqkmdafmhekned

SCOPe Domain Coordinates for d1rlza_:

Click to download the PDB-style file with coordinates for d1rlza_.
(The format of our PDB-style files is described here.)

Timeline for d1rlza_: