SCOPe 2.01: Domain d1rj2d2: 1rj2 D:819-950

Lineage for d1rj2d2 (1rj2 D:819-950)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (14 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 proteins)
   Pfam PF00169

6. Protein Dbl's big sister, Dbs [74989] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [74990] (4 PDB entries)
   SQ Q64096 624-958 # 98% sequence identity; the rat sequence Q63406 region 499-833 is 100% identical to the PDB sequence

8. Domain d1rj2d2: 1rj2 D:819-950 [104957]
   Other proteins in same PDB: d1rj2a1, d1rj2d1, d1rj2g1, d1rj2j1

Details for d1rj2d2

PDB Entry: 1rj2, 3 Å

PDB Description: Crystal structure of the DH/PH fragment of Dbs without bound GTPase

PDB Compounds: (D:) Guanine nucleotide exchange factor DBS [Fragment]

SCOPe Domain Sequences for d1rj2d2:

Sequence, based on SEQRES records:

>d1rj2d2 b.55.1.1 (D:819-950) Dbl's big sister, Dbs {Mouse (Mus musculus) [TaxId: 10090]}
tgydgnlgdlgkllmqgsfsvwtdhkkghtkvkelarfkpmqrhlflhekavlfckkree
ngegyekapsysykqslnmtavgitenvkgdtkkfeiwynareevyiiqaptpeikaawv
neirkvltsqlq

Sequence, based on observed residues (ATOM records):

>d1rj2d2 b.55.1.1 (D:819-950) Dbl's big sister, Dbs {Mouse (Mus musculus) [TaxId: 10090]}
tgydgnlgdlgkllmqgsfsvwtdhkkelarfkpmqrhlflhekavlfckkreekapsys
ykqslnmtavgitenvkgdtkkfeiwynareevyiiqaptpeikaawvneirkvltsqlq

Timeline for d1rj2d2:

• d1rj2d2 first appeared in SCOP 1.69
  
• d1rj2d2 appears in SCOP 1.75
  
• d1rj2d2 appears in SCOPe 2.02
  
• d1rj2d2 appears in the current release, SCOPe 2.08