Lineage for d1r74b_ (1r74 B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129396Family c.66.1.5: Glycine N-methyltransferase [53348] (1 protein)
  6. 2129397Protein Glycine N-methyltransferase [53349] (3 species)
  7. 2129398Species Human (Homo sapiens) [TaxId:9606] [110664] (2 PDB entries)
    Uniprot Q14749
  8. 2129400Domain d1r74b_: 1r74 B: [104829]
    complexed with bme, cit

Details for d1r74b_

PDB Entry: 1r74 (more details), 2.55 Å

PDB Description: crystal structure of human glycine n-methyltransferase
PDB Compounds: (B:) glycine n-methyltransferase

SCOPe Domain Sequences for d1r74b_:

Sequence, based on SEQRES records: (download)

>d1r74b_ c.66.1.5 (B:) Glycine N-methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
yrtrslgvaaeglpdqyadgeaarvwqlyigdtrsrtaeykawllgllrqhgcqrvldva
cgtgvdsimlveegfsvtsvdasdkmlkyalkerwnrrhepafdkwvieeanwmtldkdv
pqsaeggfdaviclgnsfahlpdckgdqsehrlalkniasmvraggllvidhrnydhils
tgcappgkniyyksdltkdvttsvlivnnkahmvtldytvqvpgagqdgspglskfrlsy
yphclasftellqaafggkcqhsvlgdfkpykpgqtyipcyfihvlkrt

Sequence, based on observed residues (ATOM records): (download)

>d1r74b_ c.66.1.5 (B:) Glycine N-methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
yrtrslgvaaeglpdqyadgeaarvwqlyigdtrsrtaeykawllgllrqhgcqrvldva
cgtgvdsimlveegfsvtsvdasdkmlkyalkerwnrrhepafdkwvieeanwmtldkdv
pqsaeggfdaviclgnsfahlpdckgdqsehrlalkniasmvraggllvidhrnydhils
tgcappgkniyyksdltkdvttsvlivnnkahmvtldytvqglskfrlsyyphclasfte
llqaafggkcqhsvlgdfkpykpgqtyipcyfihvlkrt

SCOPe Domain Coordinates for d1r74b_:

Click to download the PDB-style file with coordinates for d1r74b_.
(The format of our PDB-style files is described here.)

Timeline for d1r74b_: