SCOP 1.75: Domain d1r0aa1: 1r0a A:430-558

Lineage for d1r0aa1 (1r0a A:430-558)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (14 families)
   consists of one domain of this fold

5. Family c.55.3.1: Ribonuclease H [53099] (4 proteins)

6. Protein HIV RNase H (Domain of reverse transcriptase) [53105] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53106] (85 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582
   Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584
   Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d1r0aa1: 1r0a A:430-558 [104676]
   Other proteins in same PDB: d1r0aa2, d1r0ab1, d1r0ah1, d1r0ah2, d1r0al1, d1r0al2
   complexed with 2da, glc, gol, mg

Details for d1r0aa1

PDB Entry: 1r0a, 2.8 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase covalently tethered to dna template-primer solved to 2.8 angstroms

PDB Compounds: (A:) reverse transcriptase

SCOP Domain Sequences for d1r0aa1:

Sequence; same for both SEQRES and ATOM records:

>d1r0aa1 c.55.3.1 (A:430-558) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvd
klvsagirk

Timeline for d1r0aa1:

• d1r0aa1 first appeared in SCOP 1.69
  
• d1r0aa1 appears in SCOP 1.73
  
• d1r0aa1 appears in SCOPe 2.01
  
• d1r0aa1 appears in the current release, SCOPe 2.08