SCOPe 2.08: Domain d1pw3a_: 1pw3 A:

Lineage for d1pw3a_ (1pw3 A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
   VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family

7. Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)
   SQ NA # Bence-Jones protein JTO ! Uniprot P06317 # Ig lambda chain V-VI region SUT

8. Domain d1pw3a_: 1pw3 A: [104335]
   complexed with cd

Details for d1pw3a_

PDB Entry: 1pw3, 1.9 Å

PDB Description: crystal structure of jtor68s

PDB Compounds: (A:) immunoglobulin lambda chain variable region

SCOPe Domain Sequences for d1pw3a_:

Sequence; same for both SEQRES and ATOM records:

>d1pw3a_ b.1.1.1 (A:) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 1 [TaxId: 9606]}
nfmlnqphsvsespgktvtisctrssgnidsnyvqwyqqrpgsapitviyednqrpsgvp
drfagsidsssnsasltisglktedeadyycqsydarnvvfgggtrltvlg

Timeline for d1pw3a_:

• d1pw3a_ first appeared in SCOP 1.69
  
• d1pw3a_ appears in SCOPe 2.07