SCOPe 2.08: Domain d1p18a_: 1p18 A:

Lineage for d1p18a_ (1p18 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine PRTase [53286] (4 species)

7. Species Trypanosoma cruzi [TaxId:5693] [53287] (9 PDB entries)
   Uniprot Q27796

8. Domain d1p18a_: 1p18 A: [104053]
   complexed with 7hp, mg, prp; mutant

Details for d1p18a_

PDB Entry: 1p18, 2 Å

PDB Description: hypoxanthine phosphoribosyltransferase from trypanosoma cruzi, k68r mutant, ternary substrates complex

PDB Compounds: (A:) hypoxanthine phosphoribosyltransferase

SCOPe Domain Sequences for d1p18a_:

Sequence; same for both SEQRES and ATOM records:

>d1p18a_ c.61.1.1 (A:) Hypoxanthine PRTase {Trypanosoma cruzi [TaxId: 5693]}
yefaekilfteeeirtrikevakriaddykgkglrpyvnplvlisvlrgsfmftadlcra
lcdfnvpvrmeficvssygegltssgqvrmlldtrhsieghhvlivedivdtaltlnyly
hmyftrrpaslktvvlldkregrrvpfsadyvvanipnafvigygldyddtyrelrdivv
lrpevya

Timeline for d1p18a_:

• d1p18a_ first appeared in SCOP 1.69
  
• d1p18a_ appears in SCOPe 2.07