SCOP 1.69: Domain d1o5fh_: 1o5f H:

Lineage for d1o5fh_ (1o5f H:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (46 proteins)

6. Protein Hepsin, catalytic domain [101813] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101814] (3 PDB entries)

8. Domain d1o5fh_: 1o5f H: [103887]
   Other proteins in same PDB: d1o5fl_

Details for d1o5fh_

PDB Entry: 1o5f, 1.78 Å

PDB Description: dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa)

SCOP Domain Sequences for d1o5fh_:

Sequence, based on SEQRES records:

>d1o5fh_ b.47.1.2 (H:) Hepsin, catalytic domain {Human (Homo sapiens)}
ivggrdtslgrwpwqvslrydgahlcggsllsgdwvltaahcfpernrvlsrwrvfagav
aqasphglqlgvqavvyhggylpfrdpnseensndialvhlssplplteyiqpvclpaag
qalvdgkictvtgwgntqyygqqagvlqearvpiisndvcngadfygnqikpkmfcagyp
eggidacqgdsggpfvcedsisrtprwrlcgivswgtgcalaqkpgvytkvsdfrewifq
aikthseasgmvtql

Sequence, based on observed residues (ATOM records):

>d1o5fh_ b.47.1.2 (H:) Hepsin, catalytic domain {Human (Homo sapiens)}
ivggrdtslgrwpwqvslrydgahlcggsllsgdwvltaahcfpernrvlsrwrvfagav
aqasphglqlgvqavvyhggylpfnsndialvhlssplplteyiqpvclpaagqalvdgk
ictvtgwgntqyygqqagvlqearvpiisndvcngadfygnqikpkmfcagypeggidac
qgdsggpfvcedsisrtprwrlcgivswgtgcalaqkpgvytkvsdfrewifqaikthse
asgmvtql

Timeline for d1o5fh_:

• d1o5fh_ is new in SCOP 1.69
  
• d1o5fh_ appears in SCOP 1.71
  
• d1o5fh_ appears in the current release, SCOPe 2.08