SCOPe 2.07: Domain d1o5dh_: 1o5d H:

Lineage for d1o5dh_ (1o5d H:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (89 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d1o5dh_: 1o5d H: [103880]
   Other proteins in same PDB: d1o5dl1, d1o5dl2, d1o5dt1, d1o5dt2
   complexed with cr9

Details for d1o5dh_

PDB Entry: 1o5d, 2.05 Å

PDB Description: dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa)

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d1o5dh_:

Sequence; same for both SEQRES and ATOM records:

>d1o5dh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d1o5dh_:

• d1o5dh_ first appeared in SCOP 1.69
  
• d1o5dh_ appears in SCOPe 2.06
  
• d1o5dh_ appears in the current release, SCOPe 2.08