SCOP 1.73: Family a.238.1.1: BAR domain

Lineage for Family a.238.1.1: BAR domain

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.238: BAR/IMD domain-like [116747] (1 superfamily)
   6 helices, homodimer of 3-helical domains

4. Superfamily a.238.1: BAR/IMD domain-like [103657] (3 families)
   core: dimeric six-helical bundle; protuding long helices form aniparallel coiled coils at both bundle ends

5. Family a.238.1.1: BAR domain [103658] (2 proteins)
   sensor of membrane curvature

Proteins:

1. Amphiphysin [103659] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [103660] (1 PDB entry)

2. Endophilin-1 [140699] (3 species)
   SH3-containing GRB2-like protein 2

   1. Species Human (Homo sapiens) [TaxId:9606] [140701] (3 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [140702] (1 PDB entry)

   3. Species Rat (Rattus norvegicus) [TaxId:10116] [140700] (1 PDB entry)
      UniProt sequence of Rat species, O35179, is a fragment that does not cover the entire domain

More info for Family a.238.1.1: BAR domain

Timeline for Family a.238.1.1: BAR domain:

• Family a.238.1.1: BAR domain first appeared in SCOP 1.67, called Family h.4.14.1: BAR domain
  
• Family a.238.1.1: BAR domain appears in SCOP 1.71
  
• Family a.238.1.1: BAR domain appears in SCOP 1.75
  
• Family a.238.1.1: BAR domain appears in the current release, SCOPe 2.08