Lineage for Protein: Angiotensin converting enzyme 2, ACE2

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1211973Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 1211974Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families) (S)
  5. 1212133Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 1212134Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)

Species:

  1. 1212135Human (Homo sapiens) [TaxId:9606] [103126] (4 PDB entries)
    1. Domain for 1r42:
      • 1212139Domain d1r42a_: 1r42 A: [96968]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, zn
    2. Domain for 1r4l:
      • 1212140Domain d1r4la_: 1r4l A: [96998]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, xx5, zn
    3. Domains for 2ajf:
      1. 1212137Domain d2ajfa_: 2ajf A: [126882]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
      2. 1212138Domain d2ajfb_: 2ajf B: [126883]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
    4. Domain for 3sci:
  2. 1212141Paguma larvata [188486] (2 PDB entries)
    1. Domains for 3d0g:
      1. 1212142Domain d3d0ga_: 3d0g A: [161632]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 1212143Domain d3d0gb_: 3d0g B: [161633]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
    2. Domains for 3d0i:
      1. 1212144Domain d3d0ia_: 3d0i A: [173600]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 1212145Domain d3d0ib_: 3d0i B: [173601]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn

More info for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like: