SCOPe 2.01: Protein: Angiotensin converting enzyme 2, ACE2

Lineage for Protein: Angiotensin converting enzyme 2, ACE2

Root: SCOPe 2.01
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.92: Zincin-like [55485] (2 superfamilies)
contains mixed beta sheet with connection over free side of the sheet
Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
combines M2, M3 and M32 families of metalloproteases
the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

Protein Angiotensin converting enzyme 2, ACE2 [103125] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [103126] (3 PDB entries)
1. Domain for 1r42:
  - Domain d1r42a_: 1r42 A: [96968]
    complexed with collectrin homology domain (disordered segments), chains B, C, D and E
    complexed with cl, nag, zn
2. Domain for 1r4l:
  - Domain d1r4la_: 1r4l A: [96998]
    complexed with collectrin homology domain (disordered segments), chains B, C, D and E
    complexed with cl, nag, xx5, zn
3. Domains for 2ajf:
  1. Domain d2ajfa_: 2ajf A: [126882]
    Other proteins in same PDB: d2ajfe1, d2ajff_
    automated match to d1r42a_
    complexed with cl, nag, zn
  2. Domain d2ajfb_: 2ajf B: [126883]
    Other proteins in same PDB: d2ajfe1, d2ajff_
    automated match to d1r42a_
    complexed with cl, nag, zn
Paguma larvata [188486] (2 PDB entries)
1. Domains for 3d0g:
  1. Domain d3d0ga_: 3d0g A: [161632]
    Other proteins in same PDB: d3d0ge_, d3d0gf_
    automated match to d1r42a_
    complexed with cl, nag, ndg, zn
  2. Domain d3d0gb_: 3d0g B: [161633]
    Other proteins in same PDB: d3d0ge_, d3d0gf_
    automated match to d1r42a_
    complexed with cl, nag, ndg, zn
2. Domains for 3d0i:
  1. Domain d3d0ia_: 3d0i A: [173600]
    Other proteins in same PDB: d3d0ie_, d3d0if_
    automated match to d1r42a_
    complexed with cl, nag, ndg, zn
  2. Domain d3d0ib_: 3d0i B: [173601]
    Other proteins in same PDB: d3d0ie_, d3d0if_
    automated match to d1r42a_
    complexed with cl, nag, ndg, zn

More info for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like:

Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like first appeared in SCOP 1.67
Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like appears in SCOP 1.75
Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like appears in SCOPe 2.02
Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like appears in the current release, SCOPe 2.08