Lineage for Protein: Angiotensin converting enzyme 2, ACE2

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2963580Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 2963581Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families) (S)
  5. 2963862Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
    combines M2, M3 and M32 families of metalloproteases
    the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain
  6. 2963863Protein Angiotensin converting enzyme 2, ACE2 [103125] (3 species)

Species:

  1. 2963864Cat (Felis catus) [TaxId:9685] [389846] (1 PDB entry)
  2. 2963866Human (Homo sapiens) [TaxId:9606] [103126] (31 PDB entries)
    1. Domain for 1r42:
      • 2963897Domain d1r42a_: 1r42 A: [96968]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, zn
    2. Domain for 1r4l:
      • 2963898Domain d1r4la_: 1r4l A: [96998]
        complexed with collectrin homology domain (disordered segments), chains B, C, D and E
        complexed with cl, nag, xx5, zn
    3. Domains for 2ajf:
      1. 2963888Domain d2ajfa_: 2ajf A: [126882]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
      2. 2963889Domain d2ajfb_: 2ajf B: [126883]
        Other proteins in same PDB: d2ajfe1, d2ajff_
        automated match to d1r42a_
        complexed with cl, nag, zn
    4. Domains for 3d0g:
      1. 2963879Domain d3d0ga_: 3d0g A: [161632]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 2963880Domain d3d0gb_: 3d0g B: [161633]
        Other proteins in same PDB: d3d0ge_, d3d0gf_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
    5. Domains for 3d0h:
      1. 2963890Domain d3d0ha_: 3d0h A: [245597]
        Other proteins in same PDB: d3d0he_, d3d0hf_
        automated match to d3d0ga_
        complexed with cl, nag, ndg, zn
      2. 2963891Domain d3d0hb_: 3d0h B: [245598]
        Other proteins in same PDB: d3d0he_, d3d0hf_
        automated match to d3d0ga_
        complexed with cl, nag, ndg, zn
    6. Domains for 3d0i:
      1. 2963877Domain d3d0ia_: 3d0i A: [173600]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
      2. 2963878Domain d3d0ib_: 3d0i B: [173601]
        Other proteins in same PDB: d3d0ie_, d3d0if_
        automated match to d1r42a_
        complexed with cl, nag, ndg, zn
    7. Domains for 3sci:
      1. 2963881Domain d3scia_: 3sci A: [200605]
        Other proteins in same PDB: d3scie_, d3scif_
        automated match to d3scib_
        complexed with cl, zn
      2. 2963882Domain d3scib_: 3sci B: [196047]
        Other proteins in same PDB: d3scie_, d3scif_
        automated match to d2ajfa_
        complexed with cl, zn
    8. Domains for 3scj:
      1. 2963884Domain d3scja_: 3scj A: [249343]
        Other proteins in same PDB: d3scje_, d3scjf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 2963885Domain d3scjb_: 3scj B: [249344]
        Other proteins in same PDB: d3scje_, d3scjf_
        automated match to d3d0ga_
        complexed with cl, zn
    9. Domains for 3sck:
      1. 2963895Domain d3scka_: 3sck A: [249347]
        Other proteins in same PDB: d3scke_, d3sckf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 2963896Domain d3sckb_: 3sck B: [249348]
        Other proteins in same PDB: d3scke_, d3sckf_
        automated match to d3d0ga_
        complexed with cl, zn
    10. Domains for 3scl:
      1. 2963893Domain d3scla_: 3scl A: [249351]
        Other proteins in same PDB: d3scle_, d3sclf_
        automated match to d3d0ga_
        complexed with cl, zn
      2. 2963894Domain d3sclb_: 3scl B: [249352]
        Other proteins in same PDB: d3scle_, d3sclf_
        automated match to d3d0ga_
        complexed with cl, zn
    11. Domain for 6lzg:
    12. Domain for 6m0j:
    13. Domains for 6vw1:
      1. 2963870Domain d6vw1a_: 6vw1 A: [381985]
        Other proteins in same PDB: d6vw1e_, d6vw1f_
        automated match to d3scia_
        complexed with bma, cl, edo, nag, zn
      2. 2963871Domain d6vw1b_: 6vw1 B: [381995]
        Other proteins in same PDB: d6vw1e_, d6vw1f_
        automated match to d3scia_
        complexed with bma, cl, edo, nag, zn
    14. Domain for 7bh9:
    15. Domains for 7drv:
      1. 3085028Domain d7drvb_: 7drv B: [421345]
        Other proteins in same PDB: d7drvc_, d7drvd_
        automated match to d3scia_
        complexed with nag, zn
      2. 3085044Domain d7drva_: 7drv A: [421361]
        Other proteins in same PDB: d7drvc_, d7drvd_
        automated match to d3scia_
        complexed with nag, zn
    16. Domain for 7dx6:
    17. Domains for 7dx8:
      1. 2963886Domain d7dx8d_: 7dx8 D: [401962]
        automated match to d3scia_
        complexed with nag
      2. 2963887Domain d7dx8e_: 7dx8 E: [402033]
        automated match to d3scia_
        complexed with nag
    18. Domain for 7efp:
    19. Domain for 7efr:
    20. Domain for 7ekc:
    21. Domain for 7eke:
    22. Domain for 7ekf:
    23. Domain for 7ekg:
    24. Domain for 7ekh:
    25. Domain for 7fdi:
    26. Domains for 7l0n:
      1. 2963874Domain d7l0ne_: 7l0n E: [399565]
        Other proteins in same PDB: d7l0nb1, d7l0nb2, d7l0nd1, d7l0nd2, d7l0nh_, d7l0nl1, d7l0nl2, d7l0nm_, d7l0nn1, d7l0nn2, d7l0nr_, d7l0ns_
        automated match to d3scia_
        complexed with cl, na, nag, pg4, pg5, pge, so4, zn
      2. 2963875Domain d7l0nf_: 7l0n F: [399475]
        Other proteins in same PDB: d7l0nb1, d7l0nb2, d7l0nd1, d7l0nd2, d7l0nh_, d7l0nl1, d7l0nl2, d7l0nm_, d7l0nn1, d7l0nn2, d7l0nr_, d7l0ns_
        automated match to d3scia_
        complexed with cl, na, nag, pg4, pg5, pge, so4, zn
    27. Domain for 7lo4:
    28. Domains for 7mjm:
      1. 2963872Domain d7mjmd_: 7mjm D: [403662]
        automated match to d3scia_
        complexed with nag; mutant
      2. 2963873Domain d7mjme_: 7mjm E: [403688]
        automated match to d3scia_
        complexed with nag; mutant
    29. Domain for 7nxc:
    30. Domains for 7t9k:
      1. 3085907Domain d7t9kd_: 7t9k D: [422224]
        automated match to d3scia_
        complexed with nag
      2. 3085926Domain d7t9ke_: 7t9k E: [422243]
        automated match to d3scia_
        complexed with nag
    31. Domains for 7u0n:
      1. 3086246Domain d7u0nb_: 7u0n B: [422563]
        Other proteins in same PDB: d7u0ne_, d7u0nf_
        automated match to d3scia_
        complexed with cl, edo, mg, nag, zn
      2. 3086249Domain d7u0na_: 7u0n A: [422566]
        Other proteins in same PDB: d7u0ne_, d7u0nf_
        automated match to d3scia_
        complexed with cl, edo, mg, nag, zn
  3. 3085555Equus caballus [TaxId:9796] [421872] (1 PDB entry)

More info for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like: