SCOPe 2.08: Protein: Angiotensin converting enzyme 2, ACE2

Lineage for Protein: Angiotensin converting enzyme 2, ACE2

Root: SCOPe 2.08
Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
Fold d.92: Zincin-like [55485] (2 superfamilies)
contains mixed beta sheet with connection over free side of the sheet
Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
combines M2, M3 and M32 families of metalloproteases
the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

Protein Angiotensin converting enzyme 2, ACE2 [103125] (3 species)

Species:

Cat (Felis catus) [TaxId:9685] [389846] (1 PDB entry)
- Domain for 7c8d:
  - Domain d7c8da_: 7c8d A: [389847]
    Other proteins in same PDB: d7c8db_
    automated match to d3scia_
    complexed with zn

Human (Homo sapiens) [TaxId:9606] [103126] (34 PDB entries)

Domain for 1r42:
- Domain d1r42a_: 1r42 A: [96968]
  complexed with collectrin homology domain (disordered segments), chains B, C, D and E
  complexed with cl, nag, zn
Domain for 1r4l:
- Domain d1r4la_: 1r4l A: [96998]
  complexed with collectrin homology domain (disordered segments), chains B, C, D and E
  complexed with cl, nag, xx5, zn
Domains for 2ajf:
1. Domain d2ajfa_: 2ajf A: [126882]
  Other proteins in same PDB: d2ajfe1, d2ajff_
  automated match to d1r42a_
  complexed with cl, nag, zn
2. Domain d2ajfb_: 2ajf B: [126883]
  Other proteins in same PDB: d2ajfe1, d2ajff_
  automated match to d1r42a_
  complexed with cl, nag, zn
Domains for 3d0g:
1. Domain d3d0ga_: 3d0g A: [161632]
  Other proteins in same PDB: d3d0ge_, d3d0gf_
  automated match to d1r42a_
  complexed with cl, nag, ndg, zn
2. Domain d3d0gb_: 3d0g B: [161633]
  Other proteins in same PDB: d3d0ge_, d3d0gf_
  automated match to d1r42a_
  complexed with cl, nag, ndg, zn
Domains for 3d0h:
1. Domain d3d0ha_: 3d0h A: [245597]
  Other proteins in same PDB: d3d0he_, d3d0hf_
  automated match to d3d0ga_
  complexed with cl, nag, ndg, zn
2. Domain d3d0hb_: 3d0h B: [245598]
  Other proteins in same PDB: d3d0he_, d3d0hf_
  automated match to d3d0ga_
  complexed with cl, nag, ndg, zn
Domains for 3d0i:
1. Domain d3d0ia_: 3d0i A: [173600]
  Other proteins in same PDB: d3d0ie_, d3d0if_
  automated match to d1r42a_
  complexed with cl, nag, ndg, zn
2. Domain d3d0ib_: 3d0i B: [173601]
  Other proteins in same PDB: d3d0ie_, d3d0if_
  automated match to d1r42a_
  complexed with cl, nag, ndg, zn
Domains for 3sci:
1. Domain d3scia_: 3sci A: [200605]
  Other proteins in same PDB: d3scie_, d3scif_
  automated match to d3scib_
  complexed with cl, zn
2. Domain d3scib_: 3sci B: [196047]
  Other proteins in same PDB: d3scie_, d3scif_
  automated match to d2ajfa_
  complexed with cl, zn
Domains for 3scj:
1. Domain d3scja_: 3scj A: [249343]
  Other proteins in same PDB: d3scje_, d3scjf_
  automated match to d3d0ga_
  complexed with cl, zn
2. Domain d3scjb_: 3scj B: [249344]
  Other proteins in same PDB: d3scje_, d3scjf_
  automated match to d3d0ga_
  complexed with cl, zn
Domains for 3sck:
1. Domain d3scka_: 3sck A: [249347]
  Other proteins in same PDB: d3scke_, d3sckf_
  automated match to d3d0ga_
  complexed with cl, zn
2. Domain d3sckb_: 3sck B: [249348]
  Other proteins in same PDB: d3scke_, d3sckf_
  automated match to d3d0ga_
  complexed with cl, zn
Domains for 3scl:
1. Domain d3scla_: 3scl A: [249351]
  Other proteins in same PDB: d3scle_, d3sclf_
  automated match to d3d0ga_
  complexed with cl, zn
2. Domain d3sclb_: 3scl B: [249352]
  Other proteins in same PDB: d3scle_, d3sclf_
  automated match to d3d0ga_
  complexed with cl, zn
Domain for 6lzg:
- Domain d6lzga_: 6lzg A: [382313]
  Other proteins in same PDB: d6lzgb_
  automated match to d3scia_
  complexed with nag, zn
Domain for 6m0j:
- Domain d6m0ja_: 6m0j A: [382331]
  Other proteins in same PDB: d6m0je_
  automated match to d3scia_
  complexed with cl, nag, zn
Domains for 6vw1:
1. Domain d6vw1a_: 6vw1 A: [381985]
  Other proteins in same PDB: d6vw1e_, d6vw1f_
  automated match to d3scia_
  complexed with bma, cl, edo, nag, zn
2. Domain d6vw1b_: 6vw1 B: [381995]
  Other proteins in same PDB: d6vw1e_, d6vw1f_
  automated match to d3scia_
  complexed with bma, cl, edo, nag, zn
Domain for 7bh9:
- Domain d7bh9a_: 7bh9 A: [398415]
  Other proteins in same PDB: d7bh9e_
  automated match to d3scia_
  complexed with nag, zn
Domains for 7drv:
1. Domain d7drvb_: 7drv B: [421345]
  Other proteins in same PDB: d7drvc_, d7drvd_
  automated match to d3scia_
  complexed with nag, zn
2. Domain d7drva_: 7drv A: [421361]
  Other proteins in same PDB: d7drvc_, d7drvd_
  automated match to d3scia_
  complexed with nag, zn
Domain for 7dx6:
- Domain d7dx6d_: 7dx6 D: [401992]
  automated match to d3scia_
  complexed with nag
Domains for 7dx8:
1. Domain d7dx8d_: 7dx8 D: [401962]
  automated match to d3scia_
  complexed with nag
2. Domain d7dx8e_: 7dx8 E: [402033]
  automated match to d3scia_
  complexed with nag
Domain for 7efp:
- Domain d7efpa_: 7efp A: [421668]
  Other proteins in same PDB: d7efpb_
  automated match to d3scia_
  complexed with nag; mutant
Domain for 7efr:
- Domain d7efra_: 7efr A: [421674]
  Other proteins in same PDB: d7efrb_
  automated match to d3scia_
  complexed with nag; mutant
Domain for 7ekc:
- Domain d7ekca_: 7ekc A: [421751]
  Other proteins in same PDB: d7ekcb_
  automated match to d3scia_
  complexed with nag, zn
Domain for 7eke:
- Domain d7ekea_: 7eke A: [421771]
  Other proteins in same PDB: d7ekeb_
  automated match to d3scia_
  complexed with nag, zn; mutant
Domain for 7ekf:
- Domain d7ekfa_: 7ekf A: [421759]
  Other proteins in same PDB: d7ekfb_
  automated match to d3scia_
  complexed with nag, zn
Domain for 7ekg:
- Domain d7ekga_: 7ekg A: [421749]
  Other proteins in same PDB: d7ekgb_
  automated match to d3scia_
  complexed with nag, zn
Domain for 7ekh:
- Domain d7ekha_: 7ekh A: [421673]
  Other proteins in same PDB: d7ekhb_
  automated match to d3scia_
  complexed with nag, zn; mutant
Domain for 7fdi:
- Domain d7fdia_: 7fdi A: [421874]
  automated match to d3d0ga_
  complexed with nag

Domains for 7l0n:

Domain d7l0ne_: 7l0n E: [399565]
Other proteins in same PDB: d7l0nb1, d7l0nb2, d7l0nd1, d7l0nd2, d7l0nh_, d7l0nl1, d7l0nl2, d7l0nm_, d7l0nn1, d7l0nn2, d7l0nr_, d7l0ns_
automated match to d3scia_
complexed with cl, na, nag, pg4, pg5, pge, so4, zn

Domain d7l0nf_: 7l0n F: [399475]
Other proteins in same PDB: d7l0nb1, d7l0nb2, d7l0nd1, d7l0nd2, d7l0nh_, d7l0nl1, d7l0nl2, d7l0nm_, d7l0nn1, d7l0nn2, d7l0nr_, d7l0ns_
automated match to d3scia_
complexed with cl, na, nag, pg4, pg5, pge, so4, zn

Domain for 7lo4:
- Domain d7lo4a_: 7lo4 A: [402266]
  Other proteins in same PDB: d7lo4b1, d7lo4b2
  automated match to d3scia_
  complexed with edo, nag, zn; mutant
Domains for 7mjm:
1. Domain d7mjmd_: 7mjm D: [403662]
  automated match to d3scia_
  complexed with nag; mutant
2. Domain d7mjme_: 7mjm E: [403688]
  automated match to d3scia_
  complexed with nag; mutant
Domain for 7nxc:
- Domain d7nxca_: 7nxc A: [402522]
  Other proteins in same PDB: d7nxcb_
  automated match to d3scia_
  complexed with nag
Domains for 7t9k:
1. Domain d7t9kd_: 7t9k D: [422224]
  automated match to d3scia_
  complexed with nag
2. Domain d7t9ke_: 7t9k E: [422243]
  automated match to d3scia_
  complexed with nag
Domains for 7u0n:
1. Domain d7u0nb_: 7u0n B: [422563]
  Other proteins in same PDB: d7u0ne_, d7u0nf_
  automated match to d3scia_
  complexed with cl, edo, mg, nag, zn
2. Domain d7u0na_: 7u0n A: [422566]
  Other proteins in same PDB: d7u0ne_, d7u0nf_
  automated match to d3scia_
  complexed with cl, edo, mg, nag, zn
Domains for 7xaz:
1. Domain d7xazc_: 7xaz C: [423247]
  Other proteins in same PDB: d7xazb_, d7xazd_
  automated match to d3scia_
  complexed with nag, zn
2. Domain d7xaza_: 7xaz A: [423272]
  Other proteins in same PDB: d7xazb_, d7xazd_
  automated match to d3scia_
  complexed with nag, zn
Domain for 7xb1:
- Domain d7xb1a_: 7xb1 A: [423270]
  Other proteins in same PDB: d7xb1b_
  automated match to d3scia_
  complexed with bma, fuc, nag, zn
Domain for 7ya1:
- Domain d7ya1a_: 7ya1 A: [423294]
  Other proteins in same PDB: d7ya1b_
  automated match to d3scia_
  complexed with nag, zn; mutant

Equus caballus [TaxId:9796] [421872] (1 PDB entry)
- Domain for 7fc3:
  - Domain d7fc3a_: 7fc3 A: [421873]
    automated match to d3scia_
    complexed with nag

More info for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like

Timeline for Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like:

Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like first appeared in SCOP 1.67
Protein Angiotensin converting enzyme 2, ACE2 from d.92.1.5: Neurolysin-like appears in SCOPe 2.07