SCOP 1.71: Superfamily d.250.1: Folate-binding domain

Lineage for Superfamily d.250.1: Folate-binding domain

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.250: Folate-binding domain [103024] (1 superfamily)
   duplication: consists of two beta(2)-alpha-beta(3)-alpha subdomains swapped with the first strands

4. Superfamily d.250.1: Folate-binding domain [103025] (2 families)
   some topological similarity to Formylmethanofuran:tetrahydromethanopterin formyltransferase

Families:

1. d.250.1.1: Aminomethyltransferase folate-binding domain [103026] (3 proteins)

2. d.250.1.2: TrmE formyl-THF-binding domain [117997] (1 protein)
   dimeric biological unit; one subunit domain corresponds to one "unswapped" subdomain of the other family

More info for Superfamily d.250.1: Folate-binding domain

Timeline for Superfamily d.250.1: Folate-binding domain:

• Superfamily d.250.1: Folate-binding domain first appeared in SCOP 1.67, called Superfamily d.250.1: Aminomethyltransferase folate-binding domain
  
• Superfamily d.250.1: Folate-binding domain was called Superfamily d.250.1: Aminomethyltransferase folate-binding domain in SCOP 1.69
  
• Superfamily d.250.1: Folate-binding domain appears in SCOP 1.73
  
• Superfamily d.250.1: Folate-binding domain appears in the current release, SCOPe 2.08