Lineage for Family d.265.1.4: tRNA pseudouridine synthase TruD

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.265: Pseudouridine synthase [100877] (1 superfamily) consists of two alpha+beta subdomains with some similarity to the ferredoxin-like fold

4. Superfamily d.265.1: Pseudouridine synthase [55120] (5 families) the active site is the most conserved structural region of the superfamily and is located between the subdomains

5. Family d.265.1.4: tRNA pseudouridine synthase TruD [103021] (1 protein) natural circular permutation in the catalytic domain; insertion of the family-specific alpha+beta subdomain automatically mapped to Pfam PF01142